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This Week in Science: Mar 30, 2007

From the latest issue of Science:

A news item digs into the recent National Research Council report recommending a Global Metagenomics Initiative to better understand the microbial world through a mega-sequencing project.

A paper from lead authors Hang Yin and Joanna Slusky at the University of Pennsylvania discuss a new computational approach called CHAMP that allows users to design peptides that target specific transmembrane helices.

Also from U Penn, Joonil Jung and Nancy Bonini publish work using a Drosophila model for CAG/polyglutamine disease spinocerebellar ataxia type 3, through which they witnessed traits common to human CAG-repeat instability. They posit that "toxic consequences of pathogenic polyQ protein may include enhancing repeat instability."

From the Children's Medical Research Institute and lead author Scott Cohen comes a paper on the composition of telomerase by purifying it and performing mass spec sequencing to determine protein components and molecular size.


The Scan

Billions for Antivirals

The US is putting $3.2 billion toward a program to develop antivirals to treat COVID-19 in its early stages, the Wall Street Journal reports.

NFT of the Web

Tim Berners-Lee, who developed the World Wide Web, is auctioning its original source code as a non-fungible token, Reuters reports.

23andMe on the Nasdaq

23andMe's shares rose more than 20 percent following its merger with a special purpose acquisition company, as GenomeWeb has reported.

Science Papers Present GWAS of Brain Structure, System for Controlled Gene Transfer

In Science this week: genome-wide association study ties variants to white matter stricture in the brain, and more.