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This Week in Science: Dec 14, 2007

In news this week, London plans to build a $1 billion, 1,500-scientist biology lab in the center of the city. The collaboration between the government's Medical Research Council, two medical charities, the Wellcome Trust and Cancer Research UK, and University College London would put a number of demands on the community, including shutting down the MRC's National Institute for Medical Research.

In books, Tom Schmidt reviews The Third Domain: The Untold Story of Archaea and the Future of Biotechnology, wherein Tim Friend describes the discovery of Archaea. These "spectacular microbes," which produce methane, could help to minimize fossil fuel use in the future, writes Schmidt, adding that the book is definitely worth checking out.

Two research papers support the idea of a carboxyl-terminal domain (CTD) code, where the specific phosphorylation of certain residues of the large subunit of mammalian RNA polymerase II affects gene expression. In one, researchers use monoclonal antibodies to show that serine-7 is phosphorylated on transcribed genes. In another, they show that this phosphorylation helps the polymerase interact with the snRNA gene-specific Integrator complex.

 

The Scan

Fertility Fraud Found

Consumer genetic testing has uncovered cases of fertility fraud that are leading to lawsuits, according to USA Today.

Ties Between Vigorous Exercise, ALS in Genetically At-Risk People

Regular strenuous exercise could contribute to motor neuron disease development among those already at genetic risk, Sky News reports.

Test Warning

The Guardian writes that the US regulators have warned against using a rapid COVID-19 test that is a key part of mass testing in the UK.

Science Papers Examine Feedback Mechanism Affecting Xist, Continuous Health Monitoring for Precision Medicine

In Science this week: analysis of cis confinement of the X-inactive specific transcript, and more.