This Week in Science

In this week’s Science, researchers at the Autonomous National University of Mexico created modified Bt toxins that could kill Bt-resistant insects. Their work, which involved deleting one alpha-helix from Bt toxin Cry1Ab, showed that cadherin deletion mutations in pests confers resistance to Bt toxin, and that engineered Bt toxins can overcome this resistance.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.