This Week in Science

In Science this week, a team of UK scientists report the discovery of multiple proteins responsible for the disassembly of the replisome, the structure responsible for synthesizing complementary DNA strands during chromosome replication. They showed that a ubiquitin ligase promotes ubiquitylation of CMG, the ring-shaped DNA helicase that unwinds DNA at the start of replication. Another protein complex then associates with the ubiquitylated CMG, leading rapidly to helicase disassembly.

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The Washington Post reports on a Federal Bureau of Investigation plan to place rapid DNA analyzers at booking stations around the country.

In an editorial, officials from scientific societies in the US and China call for the international community to develop criteria and standards for human germline editing.

The US National Institutes of Health is to review studies that have received private support for conflicts of interest, according to the New York Times.

In Science this week: the PsychENCODE Consortium reports on the molecular mechanisms of neuropsychiatric disorders, and more.