This Week in Science

In Science this week, a team of academic and industry researchers report on the use of new imaging technique to understand how a key HIV protein can change its shape to facilitate infection. Using single-molecule FRET, the investigators were able to visualize the dynamic changes in the HIV-1 envelope protein Env and found that before the virus enters a host cell, the protein shifts between three different shapes.

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While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.