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This Week in Science: Sep 12, 2014

In this week's Science, a team led by Broad Institute scientists report on the identification of genetic mutations that play a role in how different people's immune systems respond to infection. They analyzed the expression of T cells from 348 healthy individuals of African, Asian, and European descent and identified differences in the activation of cytokines between individuals of different ancestry. They also found 39 mutations involved in differential immune responses and map one to the control of IL2RA, a gene associated with autoimmunity. GenomeWeb Daily News has more on this study here.

And in Science Translational Medicine, a group from the National Institutes of Health discuss emerging viral diseases and how advances in biomedical research technologies can help address such threats. Among the most important new tools available are ones for rapid genomic sequencing, which can be used to identify ways to fight against pathogens and diagnose infection at the point of care. Meanwhile, improvements in PCR make the technology especially useful in situations of diagnostic uncertainty, an issue being faced during the current Ebola outbreak in West Africa.

The Scan

Billions for Antivirals

The US is putting $3.2 billion toward a program to develop antivirals to treat COVID-19 in its early stages, the Wall Street Journal reports.

NFT of the Web

Tim Berners-Lee, who developed the World Wide Web, is auctioning its original source code as a non-fungible token, Reuters reports.

23andMe on the Nasdaq

23andMe's shares rose more than 20 percent following its merger with a special purpose acquisition company, as GenomeWeb has reported.

Science Papers Present GWAS of Brain Structure, System for Controlled Gene Transfer

In Science this week: genome-wide association study ties variants to white matter stricture in the brain, and more.