This Week in Science

In this week's Science, researchers from the University of Texas Southwestern Medical Center show how the gene-editing technology CRISPR/Cas 9 can be used to prevent muscle degeneration in a mouse model of Duchenne muscular dystrophy. The investigators removed embryos from pregnant mutant mice, injected them with CRISPR molecules designed to target and correct the dystrophin mutation, and then transferred the embryos back into wild-type female mice.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

The Wall Street Journal looks into the cost of new gene therapies.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.