This Week in Science | GenomeWeb

This Week in Science

In today's Science, proteins rule. A paper out of Jonathan Lin's lab at UCSF looks at the unfolded protein response as a result of stress at the endoplasmic reticulum. Of the three intracellular signaling branches, IRE1 plays a key role in promoting cell survival; and it, along with ATF6, another signaling branch, are turned off after prolonged ER stress.

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The White House has created a list of cuts, including to the NIH, that could be in a budget bill for this year.

The US National Institutes of Health is to allow applicants to cite preprints just as they would any other research paper, ScienceInsider reports.

Two manuscript pages handwritten by Charles Darwin are going on the auction block, according to the Los Angeles Times.

In PNAS this week: tool to track transcriptome-wide binding, evidence of balancing selection on behavior-linked genes, and more.