This Week in Science

In Science this week, a team led by Harvard Medical School's George Church report on a new way to localize RNA levels within cells using a novel fluorescent in situ RNA sequencing technique, which they dubbed FISSEQ. In FISSEQ, stably cross-linked cDNA amplicons are sequenced within a biological sample. The scientists used the approach with fibroblasts with a simulated wound-healing assay to identify cell-to-cell differences in gene expression.

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In Science this week: factors influencing retrotransposon integration sites, and more.

A bioethicist argues for the responsible use of germline gene editing.

Some breweries are using DNA-based testing to determine whether unwanted bacteria are affecting their beers, The Verge reports.

Standardized N-of-1 trials will be needed to test out personalized medicines, writes Nicholas Schork from the J. Craig Venter Institute at Nature.