This Week in Science

In Science this week, a team led by Harvard Medical School's George Church report on a new way to localize RNA levels within cells using a novel fluorescent in situ RNA sequencing technique, which they dubbed FISSEQ. In FISSEQ, stably cross-linked cDNA amplicons are sequenced within a biological sample. The scientists used the approach with fibroblasts with a simulated wound-healing assay to identify cell-to-cell differences in gene expression.

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In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.