This Week in Science

In Science this week, a team led by Harvard Medical School's George Church report on a new way to localize RNA levels within cells using a novel fluorescent in situ RNA sequencing technique, which they dubbed FISSEQ. In FISSEQ, stably cross-linked cDNA amplicons are sequenced within a biological sample. The scientists used the approach with fibroblasts with a simulated wound-healing assay to identify cell-to-cell differences in gene expression.

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In PLOS this week: new gene linked to ocular coloboma, new statistical model for interrogating gene expression networks, and more.

With a new collection, PLOS highlights negative results it has published.

A pair of researchers examines political leanings and views on genomics, finding more of a role for optimism and pessimism in people's views.

The genome of the carnivorous bladderwort is smaller than many other plant genomes, but it still holds on to important genes.