This Week in Science

In Science this week, a group led by Georg-August University Gottingen researchers report on new details about how long strands of DNA stay tightly bundled in replicating cells. Previous studies have shown that chromosomes' ability to condense during metaphase is related to activity at the tails of histones. The new findings show that during early mitosis, phosphorylation of a major histone protein recruits the chromosome passenger complex, which helps regulate the process.

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While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.