This Week in Science

Katarzyna Adamala and Jack Szostak at Massachusetts General Hospital report in Science this week that citrate appears to enable RNA replication in protocells made of fatty acid vesicles. Researchers trying to construct such protocells have found that high levels of magnesium ion within the vesicles would halt RNA replication. The duo screened a number of compounds to search for small molecules that protect the vesicles from Mg2+ leakage.

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