This Week in Science

In Science Translational Medicine this week, a team from Northwestern University reports on the use of a novel nanoparticles to deliver therapeutic RNAi agents into brain tumors in mice. Called spherical nucleic acids, the nanoparticles are essentially gold cores surrounded by a dense shell of highly oriented DNA or RNA. In the study, the researchers were able to use SNAs to carry siRNAs against a key oncogene into tumors in mouse models, where they knocked down their target and killed off cancer cells.

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Researchers test gene therapy targeting a different cancer protein in a new trial, the New York Times reports.

Pennsylvania State University researchers found that salivary microRNAs could predict which kids would have longer concussion symptoms, according to NPR.

The Associated Press reports Alex Azar, the new Department of Health and Human Services secretary nominee, made millions of dollars as a pharmaceutical executive.

In PNAS this week: immune profiling of breast cancer, transposable element patterns in rice, and more.