This Week in Science

In Science this week, a team led by Stanford University researchers report the architecture of a complete, 32-protein, RNA polymerase II transcription pre-initiation complex. The structure was determined using cryo-EM and a combination of chemical cross-linking and mass spectrometry, and showed a "marked division" in two parts — one containing all the general transcription factors and the other pol II.

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In PLOS this week: Uncovering variants associated with diabetes-related kidney disease, a sequencing study of hepatitis E viruses circulating in Cambodia, and more.

Among Sacks' books was "Awakenings," which was later made into an Academy Award-winning film.

The popularity of the #sciencemoviequote Twitter trend showcases scientists' eclectic movie tastes and knack for puns. 

The popular astrophysicist warned that apathy and even contempt for science in politics could lead to the end of informed democracy.