This Week in Science | GenomeWeb

This Week in Science

In Science this week, a multi-institute team of Japanese researchers report new details on the role of epigenetics in sex determination, finding that histone demethylation influences whether an embryo will be male or female. Specifically, the protein Jmjd1a was discovered to control the demethylation of a sex-determining gene called Sry in mice. Loss of Jmjd1a function in developing animals resulted in the reversal of their sex from male to female.

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