This Week in Science

In this week's Science, Baylor College of Medicine researcher James Lupski offers his thoughts on genome mosaicism and its implications for human health. Amid advances in sequencing technology, it is becoming apparent that individual humans are made up of a population of cells, each with its own "personal" genome, he says. This mosaicism may turn out to be more widespread than previously anticipated, raising questions as to the extent of its influence on development and disease.

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