This Week in Science

In Science this week, a team of Swiss and German researchers report new details about the regulation of Hox genes, which are clustered together in the genome and control body shape and limb development. In the study, the researchers show that during mouse limb development, Hox genes are transcribed in two waves, the first controlling arm and forearm development and the second responsible for digit formation.

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.