This Week's Science

In Science this week, researchers from McGill University reported new details about the activation of Parkin, a gene that, when mutated, is responsible for an autosomal recessive form of Parkinson’s disease. Using x-ray scattering, the team determined the crystal structure of the full-length parkin protein in rat tissue. The protein is ordinarily inactive, but they found that mutations that the disrupted two inhibitory binding interactions activated it.

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An opinion piece in the Guardian argues that President Donald Trump is uninterested in science and that might not be a bad thing for the field.

The San Francisco Chronicle reports the Veterans Affairs Health System is studying whether genetic testing can help prescribe better depression therapies.

Stat News reports that Spark Therapeutics' Luxturna is now being used to treat a wider array of patients.

In Genome Biology this week: transcription factor use among brittle stars, single-cell RNA sequencing strategy, and more.