This Week in Science

In Science this week, researchers from Stanford University reported on the discovery that the Wnt family of proteins can affect the division of embryonic stem cells based on their positions outside of the dividing cells, rather than the concentration of their signals as previously thought. The team attached Wnt3a molecules, known to maintain stem cell pluripotency, to beads that were then introduced to dividing stem cells and observed the effects using time-lapse microscopy.

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Rare gene mutations are guiding the search for drugs to manage chronic pain without opioids, according to CNBC.

The new Francis Crick Institute building can get too noisy for some researchers to concentrate, according to the Guardian.

CBS News reports that there are still many vacancies at the White House Office of Science and Technology Policy, but that it's uncertain whether they will be filled.

In Nucleic Acids Research this week: pipeline to analyze and visualize bacterial genomes, database of global set of human genomes, and more.