This Week in Science

Researchers at Genentech report in a paper published online in advance in Science this week that "loss of the tumor suppressor BAP1 causes myeloid transformation." In mouse, Bap1 gene deletion is lethal, the authors write, but "systemic or hematopoietic-restricted deletion in adults recapitulates features of human myelodysplastic syndrome." Further, the Genentech team presents evidence to suggest that BAP1 loss of function has similar consequences in human.

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An opinion piece in the Guardian argues that President Donald Trump is uninterested in science and that might not be a bad thing for the field.

The San Francisco Chronicle reports the Veterans Affairs Health System is studying whether genetic testing can help prescribe better depression therapies.

Stat News reports that Spark Therapeutics' Luxturna is now being used to treat a wider array of patients.

In Genome Biology this week: transcription factor use among brittle stars, single-cell RNA sequencing strategy, and more.