This Week in Science

In a paper published online in advance in Science this week, an international team led by investigators at the University of Cambridge shows that segment 3 of the influenza A virus contains a second open reading frame, X-ORF, which is accessed by way of ribosomal shifting. The team found that the product of this, PA-X, modulates virulence in a mouse model by decreasing pathogenicity.

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A federal grand jury has indicted Elizabeth Holmes and Ramesh Balwani for alleged wire fraud in conjunction with their activities at Theranos.

Nature News reports that some developers are nervous about GitHub's acquisition by Microsoft.

A direct-to-consumer genetic testing company sent out used spit kits, CNBC reports.

In PLOS this week: comparison of commercial bisulfite kits, new method to predict essential proteins, and more