Researchers at Case Western Reserve University report in a paper published online in advance in Science this week on their use of "the histone mark H3K4me1 to analyze gain and loss of enhancer activity genome wide in primary colon cancer lines relative to normal colon crypts." Taking this approach, the researchers identified thousands of variant enhancer loci, comprising a signature that they say is "predictive of the in vivo colon cancer transcriptome."

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

Related Posts

This Week in PLOS

This Week in Science

This Week in Science

The War Within

Citation Not Found

This Week in Science

In Cell this week: dynamics of protein profusion and localization, melanoma classification schemes, and more.

A company says it can generate likenesses of people based on their genetic profiles.

IBM's Watson is learning how to treat leukemia as a fellow at the MD Anderson Cancer Center, according to the Washington Post.

Researchers report that what scents someone picks up can reflect their complement of immune genes.