Researchers at Case Western Reserve University report in a paper published online in advance in Science this week on their use of "the histone mark H3K4me1 to analyze gain and loss of enhancer activity genome wide in primary colon cancer lines relative to normal colon crypts." Taking this approach, the researchers identified thousands of variant enhancer loci, comprising a signature that they say is "predictive of the in vivo colon cancer transcriptome."

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A research duo estimates in PLOS One the number of papers that have used misidentified cell lines.

UK's National Institute for Health and Care Excellence approves GlaxoSmithKline's SCID gene therapy despite cost.

Science reports that Brazilian researchers are petitioning for the reversal of budget cuts.

In PLOS this week: gene flow patterns in common ash, guidelines for using morpholinos in zebrafish, and more.