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This Week in Science : Feb 3, 2012

In a report published online in advance in Science this week, Duke University's Robin Hopkins and Mark Rausher discuss the strength of reinforcing selection in nature "by demonstrating strong selection favoring an allele conferring increased pigment intensity in the plant Phlox drummondii in areas of sympatry with the closely related species P. cuspidata," they write. Hopkins and Rausher also say non-random pollinator movement is behind such reinforcing selection in P. drummondii and P. cuspidata.

Over in this week's issue, researchers at the University of Washington in Seattle report "a genome representing the as-yet uncultured marine group II Euryarchaeota, assembled de novo from 1.7 percent of a metagenome sequenced from surface seawater." The team says its study demonstrates that high-coverage mate-paired sequence "can overcome assembly difficulties caused by inter-strain variation in complex microbial communities, enabling inference of ecosystem functions for uncultured members."

And in Science Signaling, researchers at the University of Utah School of Medicine and the University of Basel show that in Saccharomyces cerevisiae, "PAS kinase promotes cell survival and growth through activation of Rho1." Upon isolating PSK1 and PSK2 in a suppressor screen of a temperature-sensitive mutant of target of rapamycin 2, or TOR2, the team found that "post-translational activation of yPASK, either by cell integrity stress or by growth on nonfermentative carbon sources, also suppressed the growth defect resulting from tor2 mutation," it writes.

The Scan

Boosters Chasing Variants

The New York Times reports that an FDA advisory panel is to weigh updated booster vaccines for COVID-19.

Not Yet

The World Health Organization says monkeypox is not yet a global emergency, the Washington Post reports.

More Proposed for Federal Research

Science reports that US House of Representatives panels are seeking to increase federal research funding.

PLOS Papers on Breast Cancer Metastasis, Left-Sided Cardiac Defects, SARS-CoV-2 Monitoring

In PLOS this week: link between breast cancer metastasis and CLIC4, sequencing analysis of left-sided cardiac defects, and more.