Skip to main content
Premium Trial:

Request an Annual Quote

This Week in Science: Dec 30, 2011

Science this week named antiretroviral treatments that reduce the risk of HIV transmission its breakthrough of the year. Among the runners up are advances in microbiome research. "In 2011, researchers discerned a pattern amid the complexity," Science says of the human microbiome, adding that this year, investigators "also made other strides in understanding how diet affects the microbiome."

The journal's editors say genomic epidemiology will be an area to watch in the coming year. "Whole-genome sequences will help to determine quickly where newly emerging diseases come from, whether microbes are resistant to antibiotics, and how they are moving through a population; they will also shed light on historic epidemics," the Science staff writes.

The Scan

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.

Researchers Retrace Key Mutations in Reassorted H1N1 Swine Flu Virus With Avian-Like Features

Mutations in the acidic polymerase-coding gene boost the pathogenicity and transmissibility of Eurasian avian-like H1N1 swine influenza viruses, a PNAS paper finds.

Genome Sequences Reveal Evolutionary History of South America's Canids

An analysis in PNAS of South American canid species' genomes offers a look at their evolutionary history, as well as their relationships and adaptations.

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.