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In Science this week, researchers in the US and Sweden find functional links between beta-amyloid peptide toxicity and risk factors for Alzheimer's disease by modeling Aβ toxicity in yeast. A genome-wide screen for toxicity modifiers identified the yeast homolog of phosphatidylinositol binding clathrin assembly protein and other factors connected to Alzheimer's that had not previously been connected to Aβ toxicity.

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UK Royal Statistical Society is organizing a working group to develop guidelines for assessing COVID-19 tests, the Guardian reports.

The Washington Post reports that the White House chief of staff has asked the US Food and Drug Administration to justify the stricter standards it is seeking for a coronavirus vaccine.

President Donald Trump's "good genes" comment raises eugenics concerns, CNN reports.

In PLOS this week: genetic analysis of tremor condition, analysis of a West and Central African tree used in traditional medicine, and more.