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In a paper published online in advance in Science this week, a team led by investigators at the Broad Institute reports its analysis of whole-exome sequencing data from 74 head and neck squamous cell carcinoma tumor-normal pairs. The team found that more than 30 percent of the cases "harbored mutations in genes that regulate squamous differentiation, implicating its dysregulation as a major driver of HNSCC carcinogenesis."

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Reuters reports that Germany is seeking to sequence 5 percent of patient samples that test positive for SARS-CoV-2.

23andMe and Medscape say primary care physicians are increasingly more comfortable with discussing direct-to-consumer genetic testing results.

The publisher of the Science family of journals will allow some authors to place peer-reviewed versions of their papers into publicly accessible repositories.

In Science this week: analysis of genome-wide association studies of chronic kidney disease, and more.