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In this week's Science, Harvard University's George Church and his colleagues "present genome engineering technologies that are capable of fundamentally reengineering genomes from the nucleotide to the megabase scale." Called multiplex automated genome engineering and conjugative assembly genome engineering, or MAGE and CAGE, Church et al.'s methods "treat the chromosome as both an editable and an evolvable template, permitting the exploration of vast genetic landscapes," they write.

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23andMe has launched a new tool that estimates someone's risk of developing severe COVID-19 if infected, Bloomberg reports.

The Guardian reports that Pasteur Institute researchers are halting their development of a SARS-CoV-2 vaccine following disappointing initial results.

The Wall Street Journal reports that an increased number of younger patients have been hospitalized as the new SARS-CoV-2 strain spread across the UK.

In Cell this week: proteomic patterns among COVID-19 affected tissue samples, transcriptome atlas of developing intestines, and more.