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In a paper published online in advance in Science this week, investigators at the University of Pennsylvania School of Medicine and the University of North Carolina School of Medicine report widespread RNA-DNA differences in the human transcriptome and suggest that these "provide a yet-unexplored aspect of genome variation." By comparing human B cell RNA sequences from 27 individuals to their corresponding DNA sequences, the Penn-UNC team found "more than 10,000 exonic sites w

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Bloomberg reports AstraZeneca may conduct another study of its candidate SARS-CoV-2 vaccine after dosing error.

Moderna is applying for an Emergency Use Authorization for its coronavirus vaccine, according to the New York Times.

The National Health Service is to conduct a trial of Grail's blood-based screening test for cancer.

In PLOS this week: somatic mutation patterns of glioblastomas among Lebanese patients, phenome-wide study using UK Biobank data, and more.