This Week in Science | GenomeWeb

In a paper published online in advance in Science this week, researchers at Northwestern University and at Pennsylvania State University report the "structural basis for methyl transfer by a radical SAM enzyme." By studying crystal structures for the radical SAM enzyme RlmN — both with and without SAM — the team describes how "residue Cys 355 is S-methylated and located proximal to the SAM methyl group, suggesting that SAM involved in the initial methyl transfer binds at the s

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