This Week in Science

A news piece in this week's Science reports that ECell International (ESI), a Singapore-based company, is stopping research work on human embryonic stem cells due to increasing lack of investor interest. The time lag from lab to clinic is too long, investors say, but several companies, including Geron and ACT, are not giving up, claiming they have products in the pipeline.

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The US Food and Drug Administration has approved Alnylam's RNAi-based therapy Onpattro, according to Stat News.

Harvard Medical School's Seth Cassel and Cigall Kadoch argue in a Baltimore Sun op-ed that the recent TAILORx trial shows the potential of genomic-based medicine.

Researchers in the UK are working on using gene drives to control malaria-carrying mosquitoes, the Telegraph reports.

In PLOS this week: genetic architecture mediating gene expression, metabolomic patterns in multiple myeloma, and more.