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This Week in Science

In a paper published online in advance in Science this week, a trio of investigators at Duke University shows that the neuronal G protein-coupled catecholamine receptor OCTR-1 "controls innate immunity by regulating non-canonical unfolded protein response genes." More specifically, the Duke team found that in certain sensory neurons, OCTR-1 functions "to actively suppress innate immune responses by down-regulating the expression of non-canonical UPR [unfolded protein response ]

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Researchers tie a variant in ADAMTS3 to breathing difficulties in dissimilar dog breeds, according to Discover's D-brief blog.

Parents of children with rare genetic disease have to contend with shifts in the interpretation of genetic variants, the Wall Street Journal reports.

The Japan Times reports that researchers sequenced the genome of a woman who lived during the Jomon period.

In Science this week: single-nucleus RNA sequencing of brain tissue from individuals with autism, and more.