This Week in Science

In Science Translational Medicine this week, a public-private research collaboration led by Stephen Kingsmore at the National Center for Genome Resources in Santa Fe, NM, reports its next-gen sequencing-based screen for 448 severe recessive childhood diseases. Kingsmore et al. say that their screen scans "7,717 regions from 437 target genes ...

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.