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This Week in Science

As an expansion of a CGG repeat in the 5'-UTR of the fragile X mental retardation 1 gene leads to the up-regulation of metabotropic glutamate receptor 5-mediated signaling, an international research team sought to determine "whether a receptor subtype-selective inhibitor of mGluR5, AFQ056, improves the behavioral symptoms of FXS in a randomized, double-blind, two-treatment, two-period, crossover study of 30 male FXS patients aged 18 to 35 years." In Science Translational Medicine this week, the team reports that "seven patients with full FMR1 promoter methylation and no detectable

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Researchers trace DNA on a clay pipe found at a former slave site to a population that lives in what is now Sierra Leone, the Washington Post reports.

Two researchers report on their genetic analysis of samples from a shawl thought to belong to a victim of Jack the Ripper, ScienceInsider reports.

Japan is to release rules governing some gene-edited food, according to NHK World.

In PLOS this week: computational strategy for improving gene set analysis testing, miRNAs linked to sleep apnea, and more.