This Week in Science

As an expansion of a CGG repeat in the 5'-UTR of the fragile X mental retardation 1 gene leads to the up-regulation of metabotropic glutamate receptor 5-mediated signaling, an international research team sought to determine "whether a receptor subtype-selective inhibitor of mGluR5, AFQ056, improves the behavioral symptoms of FXS in a randomized, double-blind, two-treatment, two-period, crossover study of 30 male FXS patients aged 18 to 35 years." In Science Translational Medicine this week, the team reports that "seven patients with full FMR1 promoter methylation and no detectable

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Labs in the US and South Korea are hoping to bring the woolly mammoth back from beyond extinction, Newsweek writes.

Geneticist Adam Rutherford speaks with National Geographic about paleogenetics, race, and more.

Researchers link genetic links between education and smoking and longevity.

In PNAS this week: influence of gene environment interactions on polygenic traits, epigenetic features affecting fruit fly foraging, and more.