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In a paper published online in advance in Science this week, researchers at the Washington University School of Medicine report their use of whole-exome sequencing, followed by Sanger re-sequencing, to investigate 31 metastasizing uveal melanoma tumors, in which they identified inactivating somatic mutations in BAP1 on chromosome 3p21.1 in 26 — or 84 percent — of the samples.

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AstraZeneca has released its coronavirus vaccine trial protocol, according to the New York Times.

Time magazine looks into how liquid biopsies are changing cancer care.

According to the Guardian, more than 150 countries have signed on to a global SARS-CoV-2 vaccine plan.

In PNAS this week: similar muscle protein patterns across hypertrophic cardiomyopathy phenotypes, analysis of gene expression and brain anatomy in major depression, and more.