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In an advance online publication of Science this week, researchers at the University of Pennsylvania Medical School and their colleagues show that AMP-activated protein kinase — AMPK — "activates stress-promoted transcription via histone H2B phosphorylation." They show that "AMPK recruitment and H2B S36 phosphorylation co-localize within genes activated by AMPK-dependent pathways, and occur both in promoters and transcribed regions." AMPK-dependent H2B S36 phosphorylation, the authors write,

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The Lancet has made changes to its peer-review process in response to its recent retraction of a COVID-19-related paper, Science reports.

The New York Times reports that a series of emails show how Department of Health and Human Services officials sought to silence the Centers for Disease Control and Prevention.

A new initiative aims to move Australia's genome sequencing labs onto one system, the Sydney Morning Herald reports.

In PLOS this week: recessive mutation tied to early-onset dilated cardiomyopathy, epigenetic analysis of lung adenocarcinoma, and more.