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In an advance online publication of Science this week, researchers at the University of Pennsylvania Medical School and their colleagues show that AMP-activated protein kinase — AMPK — "activates stress-promoted transcription via histone H2B phosphorylation." They show that "AMPK recruitment and H2B S36 phosphorylation co-localize within genes activated by AMPK-dependent pathways, and occur both in promoters and transcribed regions." AMPK-dependent H2B S36 phosphorylation, the authors write,

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Russia says its candidate SARS-CoV-2 vaccine has a very high efficacy rate in an initial analysis of clinical trial data, according to the Financial Times.

Wired reports on a microbial analysis of sketches drawn by Leonardo DaVinci.

A new survey explores coronavirus vaccine hesitancy among Black and Latino individuals, the Washington Post reports.

In Nucleic Acids Research this week: the Aging Atlas database, a database of human metagenome-related metadata, and more.