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In a Science paper published online in advance this week, researchers at the New York University Center for Genomics and Systems Biology and their collaborators characterize the 3' untranslated regions in Caenorhabditis elegans. Using polyA capture, 3'RACE, full-length cDNAs, and RNA-seq, the team defines nearly 26,000 distinct 3'UTRs and frequent alternative isoforms in C. elegans; they also show that average 3'UTR length decreases as the worms age.

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