Skip to main content
Premium Trial:

Request an Annual Quote

This Week in Science: Jun 8, 2007

This week's Science is no stranger to systems biology. Stanford's Rick Myers and Caltech's Barbara Wold developed a large-scale chromatin immunoprecipitation assay (ChIPSeq) based on direct ultrahigh-throughput DNA sequencing to map, in vivo, all the binding sites (1946 total) of a transcription factor known as neuron-restrictive silencer factor (NSRF).

Another paper describes a technique called PMAGE, or "polony multiplex analysis of gene expression." Researchers at Harvard used PMAGE to detect levels of mRNA as little as one transcript per three cells, allowing them to detect the early transcriptional signs of hypertrophic cardiomyopathy in mice carrying a mutation that causes the disease.

Two studies conducted by an international team of geneticists and cardiologists used genome-wide association studies to show that about 25% of Caucasians carry a risk gene on chromosome 9 that makes them up to 40% more susceptible to various forms of heart disease.

Finally, Michael Behe is back with a slightly revised version of his theory of intelligent design. A book review criticizes the content of Behe's new book, The Edge of Evolution: The Search for the Limits of Darwinism, arguing that it’s based on faulty science.

The Scan

Alzheimer's Risk Gene Among Women

CNN reports that researchers have found that variants in MGMT contribute to Alzheimer's disease risk among women but not men.

Still Hanging Around

The Guardian writes that persistent pockets of SARS-CoV-2 in the body could contribute to long COVID.

Through a Little Spit

Enteric viruses like norovirus may also be transmitted through saliva, not just the fecal-oral route, according to New Scientist.

Nature Papers Present Method to Detect Full Transcriptome, Viruses Infecting Asgard Archaea, More

In Nature this week: VASA-seq approach to detect full transcriptome, analysis of viruses infecting Asgard archaea, and more.