This Week in Science

In Science this week, researchers describe their determination that N-terminally (Nt) acetylated Met residue could act as a degradation signal (degron), targeted by the Doa10 ubiquitin ligase, in the yeast Saccharomyces cerevisiae. They also show that Doa10 also recognized the Nt-acetylated alanaine, valine, serine, threonine, and cysteine residues.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.