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With the end of the year nigh, Science takes a look back at how its predictions for 2009 fared. It did OK saying that plant genomics was going to take off — cucumber, sorghum, maize, cassava and oil palm. For next year, Science says to keep an eye on iPS cells, exome sequencing, among other areas.

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A small, early-stage trial of a combination therapy for brain cancer reports favorable responses in two patients, according to the Guardian.

Nature News writes that viral genomic surveillance in the US faces systemic issues.

President Joe Biden is seeking an increase in federal spending, including higher budgets for the National Institutes of Health and Centers for Disease Control and Prevention.

In PLOS this week: sex-stratified genome-wide association study of chronic pain, sequencing data from Indigenous Mexican groups, and more.