This Week in Science

A paper in the early online edition of Science this weeks points to findings that suggest that lack of sleep leads to buildup of amyloid-beta protein in the brain, a hallmark of Alzheimer's disease. Monitoring the levels of this protein using in vivo microdialysis in mice, researchers led by Washington University scientists revealed that "preventing the mice from sleeping caused a 25 [percent] increase in amyloid beta levels," says a story in the Guardian.

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A federal grand jury has indicted Elizabeth Holmes and Ramesh Balwani for alleged wire fraud in conjunction with their activities at Theranos.

Nature News reports that some developers are nervous about GitHub's acquisition by Microsoft.

A direct-to-consumer genetic testing company sent out used spit kits, CNBC reports.

In PLOS this week: comparison of commercial bisulfite kits, new method to predict essential proteins, and more