This Week in Science

A paper in the early online edition of Science this weeks points to findings that suggest that lack of sleep leads to buildup of amyloid-beta protein in the brain, a hallmark of Alzheimer's disease. Monitoring the levels of this protein using in vivo microdialysis in mice, researchers led by Washington University scientists revealed that "preventing the mice from sleeping caused a 25 [percent] increase in amyloid beta levels," says a story in the Guardian.

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Consulting company McKinsey says diagnostics companies will have to combine genomic data analysis, electronic medical records, effective reimbursement strategies, and regulatory compliance in order to win.

A new report has found that researchers in Africa are still heavily dependent on funding from organizations in the US, Europe, and China, Nature News says.

An article in The Atlantic argues that the progress being made in science isn't keeping pace with the money and time being spent on research.

In Science this week: a CRISPR screen identifies sideroflexin 1 as a requisite component of one-carbon metabolism, and more.