In work out of Dave Bartel's MIT lab, researchers found that even though RNAi has not been conserved in the model budding yeast, Saccharomyces cerevisiae, it is present in other species, including S. castellii and Candida albicans. These two species use "noncanonical" Dicer proteins to make small interfering RNAs that mostly correspond to transposable elements and Y' subtelomeric repeats, they say, and when they introduced Dicer and Argonaute of S. castellii into S.