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In Science this week, researchers show that a phospholipid that binds to nuclear enzymes modifies gene transcription in response to external stimuli. Sarah Spiegel at Virginia Commonwealth University is the senior author on work that found that the lipid sphingosine-1-phosphate can also bind to histone deacetylases 1 and 2. The enzyme that creates S1P, sphingosine kinase 2, is present in the nucleus in complexes with HDAC1 and HDAC2.

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A UK study on mixing SARS-CoV-2 vaccines is expanding to include vaccines developed by additional companies, according to the Guardian.

According to Science, the US National Academy of Sciences is poised to eject two members accused of sexual harassment.

In Nucleic Acids Research this week: machine learning approach to detect DNA-bound proteins, CRISPR-based method for activating specific gene targets, and more.

The FDA and CDC call for a pause in administering Johnson & Johnson's SARS-CoV-2 vaccine while reports of rare blood clots are looked into, reports the Wall Street Journal.