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This Week in Science

In Science this week, researchers show that a phospholipid that binds to nuclear enzymes modifies gene transcription in response to external stimuli. Sarah Spiegel at Virginia Commonwealth University is the senior author on work that found that the lipid sphingosine-1-phosphate can also bind to histone deacetylases 1 and 2. The enzyme that creates S1P, sphingosine kinase 2, is present in the nucleus in complexes with HDAC1 and HDAC2.

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Bloomberg reports that the DNA-for-cash deal reported in Kentucky might be a more widespread scam.

St. Jude Children's Research Hospital scientists have treated infants with X-linked severe combined immunodeficiency using gene therapy in an early phase study.

St. Louis Public Radio reports that some African Americans are turning to DNA ancestry testing to help guide genealogical searches.

In Nature this week: a genomic analysis of the snailfish Pseudoliparis swirei, ancient DNA analysis gives insight into the introduction of farming to England, and more.