This Week in Science

In early online work in Science this week led by Harvard's Martha Bulyk and University of Toronto's Timothy Hughes, they used microarrays of all 10-base-pair sequences to look at binding specificities of 104 mouse DNA-binding proteins. Their results, they say, show a "complex landscape of binding, with virtually every protein analyzed possessing unique preferences," and with half of the proteins binding to more than one sequence.

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NPR reports that researchers in Italy are testing a gene drive aimed at controlling mosquito populations.

Researchers may experience the effects of the government shutdown for a while, the Los Angeles Times reports.

A new study finds that the majority of patients at a Tijuana clinic received a diagnosis after first-line genome sequencing, the San Diego Union-Tribune reports.

In Genome Biology this week: post-transcriptional modification-based stratification of glioblastoma, single-cell analysis of gene expression and methylation in human iPSCs, and more.