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This Week in Science: Feb 23, 2007

In today's issue of Science:

A team led by Wistar Institute scientists publish on the process of microRNA editing and demonstrate in mice that edited miRNAs silence different targets than their original forms.

In a paper from lead author Qian-Hua Shen at the Max-Planck Institute, researchers describe plant defense mechanisms, which they show to be taking place on the gene transcript level. The defense is a response to pathogen invasion and in this study is demonstrated in barley.

From Mass General comes a paper on DNA methylation, with a specific focus on methylation that occurs on the X chromosome. The authors performed a large-scale analysis to better understand the relationship between methylation, CpG island locations, and expression.


The Scan

mRNA-Based Vaccine on the Way in China

China may soon have its own mRNA-based vaccine, according to Nature News.

Arranged Killing, Fraud Alleged by Prosecutors

The Wall Street Journal reports that prosecutors allege that the co-founder of a biotech arranged to have a business associate who threatened to expose him as a fraud killed.

Whirlwind Decade of CRISPR

The New York Times looks back at the 10 years since the University of California, Berkeley's Jennifer Doudna and her colleagues published their CRISPR paper.

PNAS Papers on Blue Cone Monochromacy Structural Variants, HIV-1 Mutant, T-ALL

In PNAS this week: structural variants linked to blue cone monochromacy, HIV-1 variants affecting the matrix protein p17, and more.