This Week in PNAS

In the PNAS Early Edition this week, the University of Chicago's Yong Woo and Wen-Hsiung Li describe the relationships among the "gene clustering pattern, promoter architecture, and gene expression stability in eukaryotic genomes." In a budding yeast model, Woo and Li found that "genes with a short upstream distance tend to have low gene expression variability, and their [promoters are] flanked by strongly positioned nucleosomes and [tend] to have low nucleosome occupancy." The pair also reports that head-to-head genes, when compared with head-to-tail genes, show

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A new report highlights the potential threats posed by advances in synthetic biology, NPR reports.

A Bloomberg reporter tried to get her genetic data deleted, but found it's not so simple to do.

Johns Hopkins University's Steven Salzberg and his colleagues have come up with a new estimate for the number of human genes, Nature News reports.

In Genome Research this week: study of intra-tumor heterogeneity, workflow resources for EPIGEN-Brazil, and more.