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This Week in PNAS

In the PNAS Early Edition this week, a trio of investigators at the National Institute of Environmental Health Sciences reports the crystal structure of a human DNA polymerase λ variant, which they say forms "a natural base-base mismatch with Watson-Crick-like geometry." This variant, the authors write, is "poised to misinsert dGTP opposite a template T," such that the resulting mismatch "has Watson-Crick geometry consistent with a tautomeric or ionized base pair, with the pH depende

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US National Institutes of Health Director Francis Collins says he will avoid male-only speaker panels.

Two patients fell ill, and one subsequently died, following a fecal microbiome transplant that harbored multi-drug-resistant bacteria, according to the New York Times.

Technology Review reports that eGenesis is testing whether organs from genetically modified pigs can be transplanted into monkeys.

In Science this week: almond reference genome, and more.