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In the PNAS Early Edition this week, researchers at Harvard Medical School and their colleagues show that the Sirt6 deletion in mice "results in striking hyperacetylation of histone H3 lysine 9 and lysine 56, two chromatin marks implicated in the regulation of gene activity and chromatin structure, in various brain regions including those involved in neuroendocrine regulation" and ultimately, obesity.

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Researchers are developing a breath test to determine how severe patients' methylmalonic acidemia disease is, FierceBiotech reports.

NPR reports that vaccine developers are working on SARS-CoV-2 vaccines that are easier to store or administer than the current crop.

Reuters reports that France is to recommend that people under 55 who received one dose of AstraZeneca's SARS-CoV-2 vaccine receive a different vaccine for their second dose.