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This Week in PNAS

In the PNAS Early Edition this week, researchers at Harvard Medical School and their colleagues show that the Sirt6 deletion in mice "results in striking hyperacetylation of histone H3 lysine 9 and lysine 56, two chromatin marks implicated in the regulation of gene activity and chromatin structure, in various brain regions including those involved in neuroendocrine regulation" and ultimately, obesity.

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Researchers trace DNA on a clay pipe found at a former slave site to a population that lives in what is now Sierra Leone, the Washington Post reports.

Two researchers report on their genetic analysis of samples from a shawl thought to belong to a victim of Jack the Ripper, ScienceInsider reports.

Japan is to release rules governing some gene-edited food, according to NHK World.

In PLOS this week: computational strategy for improving gene set analysis testing, miRNAs linked to sleep apnea, and more.