This Week in PNAS | GenomeWeb

This Week in PNAS

In the PNAS Early Edition this week, researchers at the University of Pennsylvania and their colleagues in China report their "reversal of pre-existing hyperglycemia" in streptozotocin-treated, diabetic mice via the "acute and temporally controlled excision of the Men1 gene, which encodes menin." In addition, the team shows than Men1 excision improved glucose metabolism and "upregulated a group of pro-proliferative genes in pancreatic islets," which they say supports the idea that "e

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