This Week in PNAS

In PNAS this week, researchers in New York, Massachusetts, and California collaborated to show how the polyamine pathway contributes to the pathogenesis of Parkinson's disease. The team started by using fMRI to identify regions of the brain stem resistant to the disease and then profiled gene expression levels from postmortem brain regions and identified a decrease in the catabolic polyamine enzyme spermidine/spermine N1-acetyltransferase 1, related to the disease.

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An artificial intelligence-based analysis suggests a third group of ancient hominins likely interbred with human ancestors, according to Popular Mechanics.

In Science this week: reduction in bee phylogenetic diversity, and more.

The New York Times Magazine looks into paleogenomics and how it is revising what's know about human history, but also possibly ignoring lessons learned by archaeologists.

The Economist reports on Synthorx's efforts to use expanded DNA bases they generated to develop a new cancer drug.