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In the PNAS Early Edition this week, investigators in Japan show that miR-33, encoded by an intron of Srebp2, regulates HDL cholesterol in vivo. Using miR-33-deficient mice, the team found that "miR-33 repressed the expression of ATP-binding cassette transporter A1 protein, a key regulator of HDL synthesis, by mediating cholesterol efflux from cells to apolipoprotein A-I," they write.

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Novavax has begun a phase III trial of its SARS-CoV-2 vaccine, according to the New York Times.

Vox reports that the Trump Administration may limit student visas for individuals from some countries to two years.

The governor of New York says the state will conduct its own review of any SARS-CoV-2 vaccine, NPR reports.

This week in Science: Neanderthal Y chromosomes replaced by Homo sapiens Y chromosomes, and more.