This Week in PNAS | GenomeWeb

This Week in PNAS

In the PNAS Early Edition this week, investigators in Japan show that miR-33, encoded by an intron of Srebp2, regulates HDL cholesterol in vivo. Using miR-33-deficient mice, the team found that "miR-33 repressed the expression of ATP-binding cassette transporter A1 protein, a key regulator of HDL synthesis, by mediating cholesterol efflux from cells to apolipoprotein A-I," they write.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

In Science this week: metagenomic-based technique for determining protein structure, and more.

An academic laments the rise of narcissism in the sciences, the Guardian reports.

Outgoing FDA commissioner Robert Califf writes in an editorial that the agency can help boost innovation.

The Trump transition team has asked NIH Director Francis Collins to remain at his post, though it's unclear for how long that will be.