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This Week in PNAS

Afaf El-Sagheer and Tom Brown at the University of Southampton describe in this week's PNAS Early Edition a method for synthesizing chemically modified RNA constructs using click chemistry and solid-phase synthesis "to produce catalytically active hairpin ribozymes around 100 nucleotides in length." The authors suggest that "the ability to synthesize long RNA strands by a combination of solid-phase synthesis and click ligation is an important addition to RNA chemistry."

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Newsweek discusses the privacy issues raised by digital medicine.

A group of statisticians wants to eliminate researchers' reliance on 'statistical significance,' according to NPR.

In Nature this week: genetic analysis of Anatolian farmers, cotton genome analysis, and more.

Matt Hancock, the UK health secretary, is calling for the swift rollout of predictive genetic tests, the Guardian reports.